The different stages of synovitis: acute vs chronic, early vs late and non-erosive vs erosive
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Pathophysiology
Pigmented Villonodular Synovitis
Objective To evaluate the value of MRI in diagnosing pigmented villonodular synovitis(PVNS).Methods Total 12 patients of PVNS confirmed by operation and pathology were retrospectively analyzed and summarized.Results The main MRI signs of pigmented villonodular synovitis included irregular and nodular synovial proliferation,low-signal areas consistent with hemosiderin deposition,hydrarthrosis,and well-defined bony crosion.Conclusion lrregular,nodular synovial proliferation and hemosiderin deposition are the two main features of pigmented villonodular synovitis.MRI is the most valuable method for diagnosing PVNS.
Pigmented Villonodular Synovitis
Hemosiderin
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Localized nodular synovitis of the knee joint is a rare benign tumorous condition, and should be differentially diagnosed with pigmented villonodular synovitis. We report a case of localized nodular synovitis in the knee that was noted to have a pedicle and characteristic findings on MR image.
Pigmented Villonodular Synovitis
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Intermediate uveitis
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Background: Pigmented villonodular synovitis, particularly of the hip joint, has been historically treated via open synovectomy. However, an arthroscopic approach to management has been trailed successfully in recent years and has demonstrated encouraging outcomes. Case Presentation: We report the case of a 17-year-old man with pigmented villonodular synovitis of the right hip who underwent arthroscopic treatment. He remains well 5 years later with no signs of recurrence. We discuss the advantages and disadvantages of arthroscopically managed pigmented villonodular synovitis as well as the recent literature surrounding this topic. We also explain a technical tip during hip arthroscopy to access these difficult lesions. Conclusion: Arthroscopy can be used for hip pigmented villonodular synovitis treatment. These lesions may also be accessed by extending the hip to 10 degrees and releasing the traction. There is evidence to suggest that arthroscopically managed pigmented villonodular synovitis carries better outcomes and lower morbidity rates compared to an open approach in suitable cases.
Pigmented Villonodular Synovitis
Synovectomy
Hip Arthroscopy
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Vasculitis confined to the central nervous system (CNS) is a rare disease usually characterized by headache and focal neurologic symptoms. Patients with primary vasculitis of the CNS may have symptoms and laboratory findings of systemic disease such as fatigue and elevated erythrocyte sedimentation rate, but by definition, focal inflammation should not be present outside the CNS. We describe 3 patients with uveitis in association with this diagnosis. The recognition of this association adds to the complex differential diagnosis of uveitis in association with CNS disease, and indicates that "isolated" angiitis of the CNS may display clinical features outside the brain and spinal cord.
Erythrocyte sedimentation rate
Systemic vasculitis
Retinal vasculitis
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Objective:To investigate MRI features of pigmented villonodular synovitis.Methods:MRI findings of 17 patients with pathologically-proved pigmented villonodular synovitis were retrospectively analyzed.Results:Typical feature can be seen on every alignment of MRI scan in the 17 patients including nodular synovitis prolifetation,typical for hemosiderin deposition,iso-low signal on T1WI and T2WI.Conclusion:PVNS has typical feature in MRI scan.Contrasting the other diagonosis of image,MRI is of great value in diagnosing PVNS.
Pigmented Villonodular Synovitis
Hemosiderin
Feature (linguistics)
Mri scan
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Objective To explore the clinical value of using magnetic resonance imaging(MRI) to diagnose pigmented villonodular synovitis.Methods The MRI results of 12 cases of pigmented villonodular synovitis confirmed by surgery and pathology were analyzed.Results 8 cases were sporadic,4 cases multiple,10 cases diffusive and 2 cases of focal with T1WI low signals or T2WI mixed signals.Conclusion MRI can clearly show the shape and range of pigmented villonodular synovitis.
Pigmented Villonodular Synovitis
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A Case of Coccidioides Synovitis of the Knee Presents Clinically as Pigmented Villonodular Synovitis
Few cases of primary coccidioides synovitis of the knee have been reported in the literature, almost all of which have been before the widespread use of magnetic resonance imaging. We describe the case of a man presenting with findings classically associated with pigmented villonodular synovitis who was subsequently diagnosed with primary coccidioidal synovitis of the knee. This case outlines the clinical, radiographic, and pathological characteristics of coccidioidal synovitis that has yet to be outlined in the literature.
Pigmented Villonodular Synovitis
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Pigmented Villonodular Synovitis
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Uveitis is often a manifestation of sarcoidosis. Less well-recognized, however, is the development of uveitis several years before the diagnosis of systemic sarcoidosis. The possibility that presentation of uveitis is a marker for the chronicity of sarcoidosis has never been investigated. The aim of this work was to evaluate, in a Caucasian population, the epidemiology of uveitis as the primary manifestation of sarcoidosis with long-term follow-up, and the relationship of uveitis to the chronicity of sarcoidosis. The records of 1,156 Caucasian patients with histologically proven sarcoidosis, first seen in the period 1976-1992, were reviewed. In patients in whom uveitis was the primary feature of sarcoidosis, the following parameters were identified: systemic manifestations; time interval between the diagnosis of uveitis and sarcoidosis; therapy; the evolution of chest radiographic image over time; chronicity; the relationship between sarcoidosis and uveitis; and, finally, status in October 1994. In nine patients, uveitis was the reason for seeking medical treatment, resulting in the discovery of systemic sarcoidosis, which was then found to be chronic in 7 out of 9 cases. In an additional eight patients, uveitis preceded the diagnosis of systemic sarcoidosis by 1-11 yrs, and yet most subjects had systemic manifestations that went unrecognized during this time period, with chest radiograph at the time of diagnosis suggesting a long-standing chronic disease. Thus, uveitis appeared to be the primary manifestation of sarcoidosis in 17 of the 1,156 patients studied (1.5%). In conclusion, any uveitis of unknown origin may be due to sarcoidosis, although its systemic manifestations may not occur for up to 11 yrs. Uveitis patients need a very long-term follow-up, including periodic diagnostic tests for systemic sarcoidosis. Furthermore, when uveitis precedes the systemic symptoms and diagnosis of sarcoidosis by more than one year, it may be regarded as a marker of the chronicity of sarcoidosis.
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