Cryoprotection of red blood cells by a 2,3-butanediol containing mainly the levo and dextro isomers

A new industrial production method of 2, 3-butanediol is discussed in this paper. C2-4 bio-polyol is prepared by combining biological fermentation and chemical cleavage, with corn starch as raw material. In this industrial method, high purity 2,3-butanediol can be obtained after distillation and purification. Low production cost of this method provides an effective support for 2, 3-butanediol large-scaled application.

2,3-Butanediol

1,4-Butanediol

Butanediol

Corn starch

Industrial Production

10.4236/jbnb.2011.23041

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Citations (31)

Thermodynamic data for separation of ternary mixture (1,2-propanediol + 1,3-butanediol + 1,4-butanediol) by distillation

Chemical Engineering Communications (2018)

Yanyang Wu Xinchuan Qu Jiawen Zhu Kui Chen Bin Wu

Thermodynamic behaviors of ternary system (1,2-propanediol (1,2-PG) + 1,3-butanediol (1,3-BD) + 1,4-butanediol (1,4-BD)) were studied in this paper. Vapor–liquid equilibria (VLE) data of systems (1,2-PG + 1,3-BD), (1,2-PG + 1,4-BD), (1,3-BD + 1,4-BD), and (1,2-PG + 1,3-BD + 1,4-BD) were measured at 101.3 kPa. The binary interactive parameters were obtained by regressed the binary VLE data with different models. The results have shown that the Wilson model, the NRTL model and the UNIQUAC model are suitable to describe the ternary system, but the UNIFAC model is not appropriate; the residue curve map of the ternary system was obtained on the basis of the binary interactive parameters. Finally, the design and optimization of the two-column sequence distillation process were completed for separation of the ternary system. Under the optimized conditions, product amounts of 1,2-PG, 1,3-BD, and 1,4-BD can be up to 0.98, 0.90, and 0.98, respectively, after separation.

1,4-Butanediol

2,3-Butanediol

Butanediol

10.1080/00986445.2018.1423558

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Citations (2)

Cryoprotection of red blood cells by a 2,3-butanediol containing mainly the levo and dextro isomers

Cryobiology (1992)

P. Boutron

2,3-Butanediol

1,4-Butanediol

Butanediol