Nichtarteriitische vordere ischämische Optikusneuropathie: Langzeitergebnisse nach Hämodilutionstherapie
5
Citation
0
Reference
10
Related Paper
Citation Trend
Abstract:
Hintergrund In einer Langzeitstudie bei Patienten mit nichtarteriitischer, vorderer ischämischer Optikusneuropathie (VION) versuchten wir den Einfluß der Hämodilutionstherapie auf die Funktionsentwicklung, auf Rezidive und auf die Inzidenz dieser Erkrankung am Partnerauge zu untersuchen.Objective:To observe and analyze the clinical efficacy of drug adjuvant treatment of cataract.Methods:45 patients were randomly divided into treatment group 22 cases and control group 23 cases,the control group underwent small incision phacoemulsification cataract surgery,the treatment group underwent postoperative adjuvant therapy drugs,at postoperative the first and third day testing and visual acuity.Results:The 33 eyes of the treatment group,visual acuity ≥ 0.3 after 1 day had 24 eyes(72%),postoperative visual acuity≥0.3 3 days had 31 eyes(93%),the difference of the two groups was statistically significant(P0.05).Conclusion:The efficacy of drug adjuvant treatment of cataract is satisfact,it is worthy of clinical application.
Clinical efficacy
Adjuvant Therapy
Drug treatment
Cite
Citations (0)
Stroke
Cite
Citations (5)
Objective To investigate the operation with small incision for cataract patients clinical treatment effect,to evaluate its clinical value.Methods In 2010 June-2011 year in December at our hospital for treatment of 86 cases of cataract patients,were randomly divided into two groups,the observation group were treated by small incision operation,the patients of control group were treated with traditional operation,two groups of patients with postoperative improvement in visual acuity and postoperative complications were compared.Results The treatment group patients after 1D and 7d improvement in visual acuity is better than that of the control group,the difference between the two groups was significant(P 0.05);the observation group and the control group of patients with postoperative complications do not have statistical significance(P 0.05).Conclusion The small incision operation for cataract patients with better treatment effect,and can effectively improve the patient's vision,reduce the occurrence of postoperative complications,it has good clinical application value.
Cite
Citations (0)
Survey of Anesthesiology: June 2008 - Volume 52 - Issue 3 - p 123-124 doi: 10.1097/01.SA.0000307872.2249.ed
Cite
Citations (8)
Cite
Citations (1)
Purpose: To investigate the intraocular vessel density in patients with nonarteritic anterior ischemic optic neuropathy (NAION) using optical coherence tomography angiography (OCTA).Methods: Medical records of patients with NAION were retrospectively analyzed. Their age, sex, best corrected visual acuity, color vision results, mean deviation of visual field test were analyzed. Using results of OCT and OCTA that was performed at first visit within 3 weeks of symptom onset, vessel densities in eyes with NAION were evaluated by comparing contralateral unaffected eyes. Furthermore, in only affected eyes, the correlation between visual acuity at the time of diagnosis and anatomical factors such as mean vessel density and retinal nerve fiber layer (RNFL) thickness was investigated.Results: Twenty-five patients (11 males and 14 females) were enrolled in this study and the mean age was 65.92 ± 9.37 years. Whole RNFL thickness in affected eye was significantly lower than that in unaffected eye (<i>p</i> < 0.001). The average peripapillary vessel density was also significantly lower in affected eyes, 45.63% ± 7.60% compared to that in the contralateral eyes, 51.44% ± 3.40% (<i>p</i> = 0.004). In analysis of only 25 affected eyes, there was no significant correlation between each sectoral peripapillary RNFL thickness and vessel density. There was also no significant correlation between the visual acuity and the vessel density and retinal nerve fiber layer thickness in the ischemic peripapillary hemisphere. However, there was a significant negative correlation between the visual acuity and the un-ischemic peripapillary hemisphere with a coefficient of -0.608 (<i>p</i> = 0.001).Conclusions: The higher vessel density of nonaffected sector, the better visual acuity at the time of diagnosis in patients with NAION. Patency of blood supply in the preserved peripapillary intraretinal vessel density sector may affect the visual function.
Ischemic Optic Neuropathy
Optic disc
Cite
Citations (0)
Purpose: To evaluate the effect of intravitreal injection of Bevacizumab on improving visual function in patients with Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION). Methods: In a prospective interventional case series, 11 eyes with vision loss due to (NAION) in less than 15 days of attack were studied. Visual acuity, perimetry and optic nerve head changes were evaluated 1 week post-intravitreal injection of 1.25mg/0.1 mL Bevacizumab. Results: 5 of patients had improved visual acuity. In all patients optic disc edema resolved either completely or remarkably in 1 week, but there was no significant change in perimetric values. Conclusion: This case series suggest that intravitreal injection of Bevacizumab may be beneficial in treatment of NAION. Keywords : Intravitreal Bevacizumab; Non-arteritic anterior ischemic optic neuropathy; Perimetry
Cite
Citations (1)
Objective To observe the efficiency and security of enhanced external counter pulsation (EECP) as an adjunctive therapy for nonarteritic anterior ischemic optic neuropathy (NAION).Methods This was a retrospective case-control study.Forty-eight patients (48 eyes) with NAION were enrolled in this study.Thirty-two patients (32 eyes) who had been treated with blood vessel dilation and nerve nutrition drugs comprised the medicated group.Sixteen of the patients (16 eyes) in the medicated group were treated with EECP combined with blood vessel dilating and nerve nutrition drugs as EECP group.The differences were not statistically significant between groups in gender(x2 =0.000),age (t=1.096),course (t=1.613) and visual acuity (x2=0.000,P＞0.05).EECP was done once a day,one hour per time,five times a week.Fourteen eyes were treated 12 times EECP and two eyes were treated 36 times EECP within the EECP group.Systemic and ocular side effects were observed during EECP treatment.Corrected visual acuity was examined after treatment and the differences of visual acuity between medicated group and EECP group treated six times and or 12 times with EECP treatment were analyzed.The correlation of visual acuity level,and course,and acuity before treatment were analyzed.A significant improvement in visual acuity was defined as a sustained improvement of three or more visual acuity gradations.An effective of treatment was defined as a sustained improvement of two or less visual acuity gradations.No effective of treatment was defined as visual acuity dropped or showed no progress.Results After six treatments of EECP,within the 16 eyes of EECP group,two eyes achieved significant improvement,five eyes had effective improvement,and nine eyes did not show any improvement.Within the 32 eyes of medicated group,three eyes achieved significant improvement,eight eyes had effective improvement,and 21 eyes did not show any improvement.There was no statistically significant difference in vision between the two groups (x2 =0.404,P＞ 0.05).After 12 treatments of EECP,within the 16 eyes of EECP group,six eyes achieved significant improvement,nine eyes had effective improvement,and one eye did not show any improvement.Within the 32 eyes of medicated group,four eyes achieved significant improvement,10 eyes had effective improvement,and 28 eyes did not show any improvement.The difference was statistically significant comparing the vision level between the two groups (x2 =11.621,P＜0.05).The curative effect of patients negatively correlated with course of the disease (r =-0.860,P＜ 0.05),but positively correlated with visual acuity before treatment (r=1.380,P＜0.05).Skin bruises,hematoma,new retinal bleeding and other side effects did not occur in patients during EECP treatment.Conclusions Many-time therapy of EECP can improve vision of NAION patients.There is no local and general complications after a certain number of therapy.
Key words:
Optic neuropathy, ischemic/therapy; Optic neuropathy, ischemic/drug therapy; Counterpulsation/utilization
Cite
Citations (0)
To evaluate the prevalence and clinical profile of patients with biopsy-proven arteritic anterior ischemic optic neuropathy presenting with preserved visual acuity of 20/40 or better and those with an initial poor visual acuity of 20/50 or worse through a retrospective chart review.Nine of 37 patients with arteritic anterior ischemic optic neuropathy presented with a preserved visual acuity of 20/40 or better in the affected eye. All patients with preserved visual acuity had initial visual field defects that spared the central field. All 37 patients immediately received high-dose corticosteroid therapy. Visual acuity worsened by > 2 lines in one of nine patients (11%) with preserved visual acuity, with a corresponding progression of visual field constriction.Although preserved visual acuity of 20/40 or better has traditionally been associated with the nonarteritic form of anterior ischemic optic neuropathy, giant cell arteritis should still be strongly considered, especially if they have giant cell arteritis systemic symptoms.
Arteritis
Ischemic Optic Neuropathy
Cite
Citations (5)