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    PRACTICE NOTES SOFTWARE «VERTEBRAL FRACTURE ASSESSMENT» FOR DUAL-ENERGY BONE DENSITOMETER «DISCOVERY W» IN THE DIAGNOSIS OF OSTEOPOROSIS
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    Abstract:
    The authors studied the feasibility of an additional software application for dual-energy X-ray bone densitometer series «Discovery W» (HOLOGIC inc., USA). 45 patients with osteoporotic vertebral compression fractures underwent technique of «Vertebral Fracture Assessment» in one session with standard densitometry at the lumbar spine and proximal femur. This program is based on a semi-quantitative morphometry of the spine (N.K. Genant; 1993) is an alternative to radiography for the diagnosis of vertebral fractures. Determination of the index values of the vertebral bodies by this method allows identification not only explicit, but subtle compression vertebral fractures of both thoracic and lumbar spine. The methodology should be ordered by an osteoporosis specialist, evaluated by radiologist, it can be performed in one session with standard densitometry procedure. Assessment of the bone structure of the vertebral bodies by this imaging technology is not feasible.
    Keywords:
    Densitometry
    Densitometer
    Dual energy
    Vertebral Compression Fracture
    Gold standard (test)
    Digital radiography
    Bone tissue samples excised from the femoral heads of human were X-rayed together with the aluminum reference standard of density. The radiograms were scanned with the laser densitometer UltroScan XL (Pharmacia). Form the optical density profiles of bone samples the mean optical densities were determined. The optical densities were recalculated into equivalent thickness of the aluminium standard [mm Al]. Inter-measurement reproducibility of optical density determination was found to be very good (SD less than 3% of the mean). Relatively high variability (SD about 13% of the mean) was found for the optical density determination of a single bone sample X-rayed repeatedly. The inter-individual variability, which reflects the variability of bone tissue density between human subjects, was estimated as about 25% (SD as percent of the mean). We concluded that the laser densitometry performed according to our protocol provides the precise estimation of bone tissue density. Therefore, laser densitometry of bone tissue radiograms is potentially useful method for studies of bone in medical research and diagnosis.
    Densitometry
    Densitometer
    Optical density
    Bone tissue
    Citations (2)
    Currently, the radiation techniques are dominant in the diagnosis of osteoporosis, among them the dual-energy X-ray absorptiometry (DXA) is the leading. This method is based on the determination of bone mineral density. The article describes a computerized system Standart LS (Russia), which standardizes the parameters of bone mineral density, depending on the type of densitometry equipment and evaluates the results of X-ray densitometry taking into account a regional perspective. The developed program and population database of parameters of bone mineral density were the results of retrospective analysis of the dual-energy X-ray absorptiometry in 1504 women living in Kemerovo region. The dual-energy X-ray absorptiometry was performed with a bone densitometer Lunar-DPX-NT (GE Healthcare, UK). Initially, the bone mineral density of the first-fourth lumbar vertebrae was studied; then, the standardization of other parameters of densitometric systems was carried out (Hologic, Norland). The algorithm of the computer program consists of three phases: the introduction of parameters of bone mineral density, the standardization and the processing according to a type of densitometer and an age of a subject. After data processing, the values of Z-criteria are given out according to the recommendations of the International Society for Clinical Densitometry. The developed computerized system will contribute to a more accurate assessment of bone mineral density in the women, taking into account regional differences.
    Densitometer
    Densitometry
    Dual energy
    Dual-Energy X-ray Absorptiometry
    Citations (1)
    Currently, the radiation techniques are dominant in the diagnosis of osteoporosis, among them the dualenergy X-ray absorptiometry (DXA) is the leading. This method is based on the determination of bone mineral density. The article describes a computerized system Standart LS (Russia), which standardizes the parameters of bone mineral density, depending on the type of densitometry equipment and evaluates the results of X-ray densitometry taking into account a regional perspective. The developed program and population database of parameters of bone mineral density were the results of retrospective analysis of the dual-energy X-ray absorptiometry in 1504 women living in Kemerovo region. The dual-energy X-ray absorptiometry was performed with a bone densitometer Lunar-DPX-NT (GE Healthcare, UK). Initially, the bone mineral density of the first-fourth lumbar vertebrae was studied; then, the standardization of other parameters of densitometric systems was carried out (Hologic, Norland). The algorithm of the computer program consists of three phases: the introduction of parameters of bone mineral density, the standardization and the processing according to a type of densitometer and an age of a subject. After data processing, the values of Z-criteria are given out according to the recommendations of the International Society for Clinical Densitometry. The developed computerized system will contribute to a more accurate assessment of bone mineral density in the women, taking into account regional differences.
    Densitometer
    Densitometry
    Dual energy
    Dual-Energy X-ray Absorptiometry
    Citations (0)
    Methods of bone mineral density measurement are presented. Radiological photogrammetry, single photon absorptiometry, dual photon absorptiometry and dual energy X-ray absorptiometry are described. Mode of work of densitometers and their characteristics ares presented. Modern development of densitometric equipment and possible application in diagnosing of osteoporosis is discussed.
    Densitometer
    Densitometry
    Dual energy
    Dual-Energy X-ray Absorptiometry
    Citations (0)
    Densitometry at Cinecolor matches use as closely as possible. To this end, densitometry of material to be used on optical printers is on a “specular densitometer,” and densitometry of sound tracks is on a “sound reproducer densitometer.” This paper describes these two densitometers.
    Densitometer
    Densitometry
    Specular highlight
    Citations (0)