The effects of arterial wall remodelling on the wall shear stress distributions in vascular bypass grafts

The effects induced by a mild arterial stenosis on the wall shear stress is theoretically investigated. Distribution of shear stress along canine femoral artery and during the cardiac cycle is calculated simulating both the physiological state of the artery and the stenotic condition. The presence of a stenosis in the vessel significantly influences the shape of shear stress distribution. Shear stress in the stenotic case approximately increases of 30% both for the mean and the peak values.

Cardiac cycle

10.1109/iembs.1992.5761041

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Citations (4)

Particle-hemodynamics modeling of the distal end-to-side femoral bypass: effects of graft caliber and graft-end cut

Medical Engineering & Physics (2003)

P. Worth Longest Clement Kleinstreuer

Intimal hyperplasia

10.1016/s1350-4533(03)00124-3

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Citations (36)

Effects of the flexibility of the arterial wall on the wall shear stresses and wall tension in abdominal aortic aneurysms

HAL (Le Centre pour la Communication Scientifique Directe) (2005)

Anne‐Virginie Salsac María Teresa Fernández Jean‐Marc Chomaz Patrick Le Tallec

Tension (geology)

Arterial wall

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Citations (2)

Blood Flow and Arterial Disease

Springer eBooks (2010)

Nicolaas Westerhof Nikolaos Stergiopulos Mark I. M. Noble

10.1007/978-1-4419-6363-5_28

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Citations (2)

Flow waveform effects on end-to-side anastomotic flow patterns

Journal of Biomechanics (1998)

C. Ross Ethier David A. Steinman Xuping Zhang S. R. Karpik M. Ojha

Intimal hyperplasia

10.1016/s0021-9290(98)00059-1

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Citations (103)

HEMODYNAMIC SHEAR EFFECTS ON THE LINING OF THE ARTERIAL WALL

Elsevier eBooks (1988)

Morton H. Friedman

Arterial wall

10.1016/b978-0-08-036232-8.50171-7

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Citations (0)

Negative Correlation of Wall Thickness With Wall Blood Pressure in a Patient-Specific Atherosclerotic Coronary Artery: A Case Report

ASME 2008 Summer Bioengineering Conference, Parts A and B (2012)

Biyue Liu Jie Zheng Richard G. Bach Dalin Tang

There are two major hemodynamic stresses imposed at the blood-arterial wall interface by flowing blood: the wall shear stress (WSS) acting tangentially to the wall, and the wall pressure (WP) acting vertically to the wall. These forces influence the artery wall metabolism and correspond to the local modifications of artery wall thickness, composition, microarchitecture, and compliance [2]. The role of flow wall shear stress in atherosclerosis progression has been under intensive investigation [4], while the impact of local blood pressure on plaque progression has been under-studied.

Arterial wall

Vascular wall

Lateral wall

10.1115/sbc2012-80039

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Flow behaviour in a novel graft/artery junction

Michael T. Walsh Thomas P. O’Brien Liam Morris P.D. Devereux Tim M. McGloughlin

The restoration of blood supply to diseased limb extremities is possible using vascular bypass grafts. However, such procedures have moderate patency rates. This study investigates a novel bypass graft / artery configuration. Numerical investigations using computational fluid dynamics are carried out. Results are presented both qualitatively, using velocity vectors and velocity contours, and quantitatively using wall shear stresses. Results demonstrate the effectiveness of the novel bypass graft in reducing wall shear stresses in the junction area and delivering flow patterns similar to the flow patterns expected in a pre-operative idealised healthy artery. It is concluded that the novel graft could lead to significantly improved patency rates in vascular bypass graft procedures.

Blood supply

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