Opinion: A serious issue with the standardization of the adenovirus-based COVID-19 vaccines?

Presently, adenovirus-based vaccines are dosed by viral particle or viral genome number. Given that the ratio of these to the actually infectious units, the active principle of the vaccines, can vary by several orders of magnitudes in a given preparation this is criticized by the author as inappropriate. Based on existing data from both, animal as well as human vaccination trials, the commentary details this problem and proposes solutions to the problem.