NaI/TBHP-promoted reaction of indole-2-thiones with arylsulfonyl hydrazides: construction of achiral axial 3,3′-biindole-2,2′-dibenzenesulfonothioate derivatives

A new method for the synthesis of achiral axial 3,3′-biindole-2,2′-dibenzenesulfonothioate derivatives from indole-2-thiones with arylsulfonyl hydrazides promoted by NaI/TBHP is disclosed. The reaction proceeded smoothly without a transition-metal catalyst under mild conditions, and provides a novel and efficient one-pot strategy to synthesize 3,3′-biindole-2,2′-dibenzenesulfonothioate derivatives.