One pot electrochemical synthesis of 10,10′-bisvindoline by an oxidation-reduction sequence

Abstract Anodic oxidation of vindoline, 1, at the controlled potential of Pt-electrode (E=1.1 V vs. SCE) followed by the reduction (E=0.0 V vs. SCE) of the formed intermediate 2a gave 10,10′-bisvindoline, 2 , in 60% yield.