Effects of Early-Onset Radiofrequency Electromagnetic Field Exposure (GSM 900 MHz) on Behavior and Memory in Rats

Female Wistar rats, from an age of 14 days to 19 months, were exposed in the head region for 2 h per day, 5 days per week, to a GSM-modulated 900 MHz radiofrequency electromagnetic field (RF-EMF). The average specific absorption rates (SAR) in the brain were 0 (sham), 0.7, 2.5 and 10 W/kg. To ensure a primary exposure of the head region, rats were fixed in restraining tubes of different sizes according to their increasing body weight. During the experiment, a set of 4 behavioral and learning tests (rotarod, Morris water maze, 8-arm radial maze, open field) were performed 3 times in juvenile, adult and presenile rats. In these tests, no profound differences could be identified between the groups. Only presenile rats of the cage control group showed a lower activity in two of these tests compared to the other groups presumably due to the lack of daily handling. The rotarod data revealed on some testing days significantly longer holding times for the sham-exposed rat vs. the exposed rat, but these findings w...