Design, syntheses and potentiating activities against methicillin resistant Staphylococcus aureus of cyclic analogs of LY301621
1997
Abstract Previous SAR studies of the diastereomers of LY301621 suggested the importance of a β-turn conformation for biological activity. In the present study, cyclic analogs were designed and synthesized that possess Type II and II' β-turns. Their biological activity will be discussed.
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