Family history of diabetes is associated with hypertriglyceridaemia in healthy normal-weight children.

Studies in adults show that family history of diabetes correlates with the increase of serum triglyceride levels (1) and that hypertriglyceridaemia is associated to insulin insensitivity (2). These findings suggest that hypertriglyceridaemia is an early biomarker of inadequate insulin secretion and action; results that highlight the role of triglyceride as an early marker of insulin insensitivity and metabolic risk.