Genetically modified nk cell line having novel chimeric antigen receptor-encoding gene transduced therein, and use thereof
2019
The present invention provides a genetically modified immune cell and a use thereof, the genetically modified immune cell having, in order to enable more efficient immunotherapy for solid tumors, a host immune cell transformed so as to express a cancer antigen-specific chimeric antigen receptor (CAR) protein comprising a cancer antigen-specific monoclonal antibody or a functional fragment thereof, a transmembrane domain, and a CD3ζ domain of a T cell receptor.
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