Computational prediction and experimental validation of the activator function of 2C-β-d-glucopyranosyl-1,3,6,7-tetrahydroxyxanthone on pancreatic and hepatic hexokinase

AbstractThis study identifies and validates hexokinase type 4 (HK4), an isozyme of hexokinase in the liver and pancreas, as an important target of 2C-β-d-glucopyranosyl-1,3,6,7-tetrahydroxyxanthone...