APO B/APOA1 RATIO IS STATISTICALLY THE BEST PREDICTOR OF MYOCARDIAL INFARCTION COMPARED TO OTHER LIPID RATIOS

The aim of our work was to study the predictive val ue of various lipid ratios in patients with Myocard ial Infarction (MI). Study group with 60 patients of do cumented myocardial infarction and 60 healthy controls were enrolled. Extended lipid profile with Serum A polipoprotein A and Apolipoprotein B was undertaken for each subject. Lipid ratios of LDL/HDL, TC ‐ HDL/HDL, TG/HDL-C and Apo B/Apo A1were calculated and statistically evaluated to determine the best predictor of MI amongst them. All the abo ve ratios were significantly higher in cases compared to the controls (p<0.0001for all). On multiple regr ession analysis, the best predictor for MI was Apo B/Apo A 1 ratio. The coefficient Beta for ApoB/Apo A1 was 0.691 with t value of 9.916 showing highly signific ant prediction of MI (p<0.000). Based on our findin gs we advocate the use of ApoB/Apo A1 ratio in Indian Population for assessing risk of MI.