DRUG UTILIZATION STUDY OF ANTIPSYCHOTICS AND ITS COMMON ADR’S IN THE PSYCHIATRY OPD OF OHRC

Objective To determine the safety and efficacy of the drug used. To analyze drug utilization pattern. To identify the ADR’s caused by psychotropic drugs Methods: IRB approval was obtained and a hospital based cross sectional study was carried out at psychiatric OPD of OHRC. 500 prescriptions were collected and information was recorded in data collection form and analyzed. Results: From 500 prescriptions, 46.8% of prescriptions were of males and 53.2% of prescriptions were of females. Schizophrenia accounted for 29.6% of prescriptions whereas, 38.4% were of mood disorder, 21.6% were of anxiety and 10.4% were of other disorders.Drug Utilization Pattern in different psychiatric disorders : Mood disorder was the most common diagnosis followed by schizophrenia and anxiety. In mood disorder, the most commonly prescribed drug was escitalopram and the least commonly prescribed drug was fluoxetine. In schizophrenia the most commonly prescribed drug was diazepam and the least commonly prescribed drug was aripiprazole. In anxiety, the most commonly prescribed drug was clonazepam and the least commonly prescribed drug was haloperidol. PDD/DDD ratio of escitalopram and sodium valproate was nearer to one. Conclusion: In this study we get to know about the current prescribing trend of the psychotropic drugs and we also came to know the corresponding ADR'S of the drugs prescribed.