Makomotindoline from Makomotake, Zizania latifolia infected with Ustilago esculenta

Abstract Makomotindoline ( 1 ) was isolated from Makomotake, Zizania latifolia infected with Ustilago esculenta . The structure was determined by the interpretation of spectroscopic data and synthesis. Makomotindoline ( 1 ), its l -Glc isomer ( 2 ) and its aglycon ( 3 ) were synthesized and their effects on rat glioma cells showed adverse effects on the cell growth.