A non-uniformity correction method of regularization image based mri

The present invention provides a regularized non-uniformity correction method based on the MRI image, by improving low-pass filtering method, to select a partial region gradation values ​​differ little low-pass filtering, to obtain an initial estimate of a non-uniform field, a positive then the polynomial method of extrapolation to obtain a full image of the inhomogeneous field estimation. The present invention determines a region of interest is filtered to avoid boundary effects global image filtering methods; regularization method of fitting can be guaranteed not to over-fitting in the case of improving the fit orders.