The absolute configuration of a new aminoalkylphenol derived from ( R )-(–)-2-phenylglycine

The chiral amino­alkyl­phenol N-[(S)-1-(5-methyl-2-hydroxy­phen­yl)eth­yl]-N–[(R)-2-hydr­oxy-1-phenyl­ethyl]amine, C17H21NO2, was synthesized starting from R-(-)-2-phenyl­glycine. The corresponding hydro­chloride salt was prepared and crystallized as an ethyl acetate solvate, affording N-[(R)-2-hydr­oxy-1-phenyl­ethyl]-N-[(S)-1-(5-methyl-2-hydroxy­phen­yl)eth­yl]aminium chloride ethyl acetate solvate, C17H22NO2+·Cl−·C4H8O2, and the absolute configuration of the new stereogenic centre determined, from which that of the chiral amino­alkyl­phenol was inferred. The dihedral angle between the two aromatic rings is 40.74 (11)°.