Anticancer Property of Lanthanide Sulfate Nanostructure Against Neuroblastoma-Neuro2a Cell Line

A novel lanthanum (III) complex with 8-Hq = 8-hydroxy quinoline and phen-dione = 1,10-phenanthroline-5,6-dione was synthesized using the reflux method. The complex was characterized using elemental analyses, cyclic voltammetry technique, electronic absorption spectroscopy, H-NMR spectroscopy, X-ray powder diffraction, and scanning electron microscopy. Then, La2O2(SO4) nanostructure (NS La-s) was obtained from the lanthanum (III) complex as a precursor after calcination at 700 °C for 4 h. The thermal stability of nanostructure was determined by the thermal gravimetric method. SEM results showed that the morphology of La2O2(SO4) was spiral-like. The cytotoxicity of La-s NS was studied using cell viability assay on neuroblastoma-N2a cell line culture. The results ranked the cytotoxicity activity of La-s NS in N2a cell line to IC50 =  ~ 22 μg mL− 1.