Intermolecular Alkene Difunctionalization via Gold Catalyzed Oxyarylation.

The g old-catalyzed intermolecular oxyarylation of alkene is reported. This work employed the oxidative addition of aryl iodide to Me-DalphosAu +  for the formation of Au(III)-Ar intermediate.  The better binding ability of alkene over O nucleophiles ensured the success of intermolecular oxyarylation, giving desired products with broad substrate scope and high efficiency (>50 examples with up to 95% yield).  "One-pot" converting of methoxy group into other nucleophiles allowed achieving alkene difunctionalization with C-N, C-S, and C-C bonds construction under mild conditions.