To Investigate the Effect of Catheter Drainage and Urokinase Dissolution for Severe Ventricular System Hemorrhage

Objective: To investigate the decrease of mortality and disability rate of severe ventricular system hemorrhage by catheter drainage and UK dissolution. Methods: From January 2015 to January 2020, 78 cases of primary severe ventricular hemorrhage and 47 cases of thalamic hematoma had broken into the ventricular system by admitted, all of which were caused by hypertension arteriosclerosis. A respectively adopt the double eminence F10 silicone tube line hemorrhage or hemorrhage drainage, drain and intraoperative all press automatic drainage device, and at the same time CT directional line thalamic hematoma drainage, pipe emptying and postoperative introcerebral hematoma and interior cavity at different times each injection urokinase solute 30000-50000 units, and lumbar puncture or with lumbar cistem catheter drainage, large cavity of thalamic hematoma and the original secondary intraventricular hemorrhage drainage time respectively for 3-4 d and 4-5 d, an average of 4.5 d extubation time. Results: After 6 months of follow-up, GOS and ADL grading were used to evaluate the recovery and self-care ability. GOS grading was 5points in 72 cases, 4 points in 41 cases, 3 points in 12 cases. ADL grading was Grade I in 69 cases, Grade II in 40 cases, Grade III in 5 cases, Grade IV in 6 cases, and Grade V in 5 cases (including 3 deaths). Among the 3 cases who died after operation, either 2 case suffered from primary whole ventricular hemorrhage combined with cerebral hernia, 1 case suffered from secondary hemorrhage combined with respiratory and circulatory failure caused by dilated hemocast of four ventricles. Sometime whith association communicating hydrocephalus in 3 cases that is underwent brain-peritoneal cerebrospinal fluid shunt. Conclusion: Empty and drainage of ventricular system hemorrhage and paraventricular thalamic hematoma which is can significantly reduce the morbidity and mortality.