A New Risk Score for Patients With a Normal or Non-Diagnostic ECG Admitted to a Chest Pain Unit

Introduction and objectives Patients admitted to chest pain units are usually classified on the basis of the results of non-invasive tests. However, the large number of potential patients places a strain on limited resources. Our aim was to identify clinical variables that may help determining the risk of coronary artery disease. Patients and method We studied 365 consecutive patients admitted to the chest pain unit at our institution, all of whom had an ECG that did not show significant changes in repolarization. Results The patients' mean age was 62.3 years. Independent predictors of coronary artery disease were: typical chest pain, aspirin use, diabetes, and age >64 years. A risk score obtained by combining these 4 factors was related to the occurrence of a clinical event during the patient's stay in the chest pain unit, to coronary artery disease prevalence (which varied from 3.9% in those with a score of 0 to 66.7% in those with a score of 4), to all-cause mortality, and to the development of acute coronary syndrome during the 6-month follow–up period. Conclusions The presence of typical chest pain, aspirin use, diabetes, and an age >64 years is associated with an increased probability of coronary artery disease in patients admitted to chest pain units. A risk score obtained by combining these four factors may be clinically useful and help optimizing resource management.