An Automated Controls for the Liver Transplant Preservation Machine
2020
With the current method of liver preservation through chilled preservation solution, surgeons are restricted with a time constraint to complete a liver transplant, which greatly decreases the donor pool of liver grafts. The objective of this study is to develop, assemble, and test a cost effective medical machine that is designed to prolong the preservation time span of a donate liver that would be used for transplantation. The medical machine should be able to maintain physiological parameters similar to the body. The machine must be able to maintain a pH level of 6.8 to 7.4, a temperature level of 36.5 to 37.5 °C, and a continuous fluid flow within the machine, with a flow rate of 200 to 300 mL/min for the hepatic artery and 600 to 900 mL/min for the portal vein. The pH module system was able to produce accurate pH readings and serve as a reliable, autonomous pH adjuster. For the flow rate, the machine will be able to maintain the desired rate for at least 8 hours. Furthermore, the monitoring system has accurately displayed the parameters that was needed and was able to save patient records through a database system.
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