Atorvastatin does not affect the pharmacokinetics of cyclosporine in renal transplant recipients

Monica Hermann,Anders Åsberg,Hege Christensen,Jan Leo Egge Reubsaet,Hallvard Holdaas,Anders Hartmann

Atorvastatin does not affect the pharmacokinetics of cyclosporine in renal transplant recipients

2005

Monica Hermann
Anders Åsberg
Hege Christensen
Jan Leo Egge Reubsaet
Hallvard Holdaas
Anders Hartmann

Objective The aim of the present study was to evaluate the possible influence of atorvastatin on the pharmacokinetics of cyclosporine (INN ciclosporin) and its main metabolites, AM1 and AM9, in renal transplant recipients.

Keywords:

Diabetes mellitus
Ciclosporin
Atorvastatin
Medicine
Urinary system
Transplantation
Hydroxymethylglutaryl-CoA reductase
Pharmacology
Pharmacokinetics
Kidney

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