A reversible carnitine palmitoyltransferase (CPT1) inhibitor offsets the proliferation of chronic lymphocytic leukemia cells

Chronic lymphocytic leukemia (CLL) cells display altered lipid metabolism and utilize fatty acid oxidation for their energy needs. We explored, on leukemic cells exposed in vitro to activating microenvironment-mimicking stimuli, the effects of a reversible inhibitor of carnitine-palmitoyl