Adrenal leiomyosarcoma: a rare clinical entity

Adrenal leiomyosarcomas are very rare tumors of mesenchymal origin. We report a 61-year-old male case, with an incidentally diagnosed adrenal mass. MRI revealed a heterogeneous 10cm mass, potentially malignant and the patient underwent an open left radical adrenalectomy. Microscopically, spindle cell type neoplasia was seen. Immunohistochemically, the tumor cells were positive for smooth muscle actin and desmin and the final diagnosis was a well-differentiated primary adrenal leiomyosarcoma. During his 2-year follow-up appointment he had multiple metastases and progressive disease, for which he is still receiving chemotherapy.