Predicting platinum resistance in primary advanced ovarian cancer patients with an in vitro resistance index.
2012
Purpose
We aimed to identify primary platinum resistance in epithelial ovarian cancer (OC) patients with FIGO stage III–IV disease by an in vitro drug-response assay and to correlate the findings with clinical response. We considered whether neoadjuvant chemotherapy or anatomic sample site and tumor heterogeneity would influence the results.
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