Effect of Methotrexate on an In Vitro Patient-Derived Model of Proliferative Vitreoretinopathy

Dhanesh Amarnani,Arturo Israel Machuca-Parra,Lindsay L. Wong,Christina K. Marko,James A. Stefater,Tomasz P. Stryjewski,Dean Eliott,Joseph F. Arboleda-Velasquez,Leo A. Kim

Effect of Methotrexate on an In Vitro Patient-Derived Model of Proliferative Vitreoretinopathy

2017

Dhanesh Amarnani
Arturo Israel Machuca-Parra
Lindsay L. Wong
Christina K. Marko
James A. Stefater
Tomasz P. Stryjewski
Dean Eliott
Joseph F. Arboleda-Velasquez
Leo A. Kim

Purpose The purpose of this study was to develop a method for isolating, culturing, and characterizing cells from patient-derived membranes in proliferative vitreoretinopathy (PVR) to be used for drug testing.

Keywords:

Retinal detachment
Cancer research
Methotrexate
Proliferative vitreoretinopathy
Biology
Cell type
Cell
Glial fibrillary acidic protein
Cell migration
Anatomy
Programmed cell death
In vitro
Molecular biology
Apoptosis

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