FRI0076 LACTATE/SLC5A12-induced metabolic signalling network: a new target in rheumatoid arthritis

BackgroundRA is a systemic-autoimmune-disease characterized by chronic inflammation of the synovial-joints. Up to 30–40% of patients do not respond to treatment and current biomarkers are largely insensitive at predicting disease progression and response to treatment. It is well recognised that RA-s