WU Polyomavirus Infections in Children in Fuzhou, China

In this study, we tested for the presence of WUV in children with respiratory tract infection in Fuzhou, Fujian, China. Nasopharyngeal aspirates (NPA) were collected from children with respiratory tract infection from Nov. 2007 to Oct. 2008. A total of 58 clinical respiratory tract samples were tested for WUV by using PCR method. The positive products were sequenced and compared with those in Genbank. 4 of 58 were positive (WUV was 6.9%). All of children who were positive for WUV had respiratory manifestations. WUV was tested positive in the sputum and vomited specimen, and in the fecal specimen of one outpatient child who also had acute gastroenteritis. Co-infections with other respiratory viruses were found in 3 (75.0%) of WUV positive NPA samples. Polyomavirus WUV infection may be associated with upper and lower respiratory infection. WUV might also be transmitted through the gastrointestinal tract.