Cheminformatics and virtual screening studies of COMT inhibitors as potential Parkinson’s disease therapeutics

Kalliopi Moschovou,Georgia Melagraki,Thomas Mavromoustakos,Lefteris C. Zacharia,Antreas Afantitis

Cheminformatics and virtual screening studies of COMT inhibitors as potential Parkinson’s disease therapeutics

2020

Kalliopi Moschovou
Georgia Melagraki
Thomas Mavromoustakos
Lefteris C. Zacharia
Antreas Afantitis

ABSTRACTIntroduction: Parkinson’s Disease (PD) is a neurodegenerative central nervous system (CNS) disorder characterized by dopaminergic neuron degeneration with consequent reduction in striatal d...

Keywords:

Bioinformatics
Biology
Virtual screening
Cheminformatics
Disease
Central nervous system
dopaminergic neuron
Parkinson's disease
Catechol-O-methyl transferase

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