Postural instability, the absence of sexual intercourse in the past month, and loss of libido are predictors of sexual dysfunction in Parkinson’s disease

Abstract Objective To determine the prevalence and predictors of sexual dysfunction (SD) in Parkinson's disease (PD) patients. Background Assessments of SD in the professional literature is limited. Understanding the predictors of SD can help physicians focus on this problem in vulnerable patients. Method A total of 60 PD patients and 60 controls answered the Arizona Sexual Experiences Scale-Thai Version (ASEX-Thai) and the Hamilton Depression Rating Scale (HAMD) questionnaires, and were asked on 3 additional sets of questions about premature ejaculation (PE), dyspareunia, and hypersexual disorders. Result The prevalence of SD in PD patients and controls was 81.6% and 48.3% respectively ( p p p  = 0.028), and HAMD item 14 ( p  = 0.021), predicting SD with the OR of 12.2, 5.5, and 5.0 respectively. Conclusions SD in PD is common and usually occurs with depression. Absence of SI in the past month, PI, and loss of libido are predictors of SD in PD. A simple and quick screening of SD can be routinely performed by inquiring patients about the frequency of SI and the examination of the pull test. Detailed assessment of sexual functioning and depression may guide physicians in proper management.