Improved Synthesis of [11C]COU and [11C]PHXY, Evaluation of Neurotoxicity, and Imaging of MAOs in Rodent Heart

Allen F. Brooks,Anthony J. Mufarreh,Xia Shao,Tanpreet Kaur,Jenelle Stauff,Janna Arteaga,Michael R. Kilbourn,Peter Scott

Improved Synthesis of [11C]COU and [11C]PHXY, Evaluation of Neurotoxicity, and Imaging of MAOs in Rodent Heart

2020

Allen F. Brooks
Anthony J. Mufarreh
Xia Shao
Tanpreet Kaur
Jenelle Stauff
Janna Arteaga
Michael R. Kilbourn
Peter Scott

The radiotracers [11C]COU and [11C]PHXY are potential PET imaging agents for in vivo studies of monoamine oxidases (MAOs), as previously shown in rodent and primate brain. One-pot, automated method...

Keywords:

Rodent
Neurotoxicity
Medicine
Pharmacology

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