MP22-13 IMPACT OF RELATIONAL COHESION AND SEXUALITY ON THE QUALITY OF LIFE OF PATIENTS TREATED WITH GONADOTROPIN-RELEASING HORMONE (GNRH) AGONIST FOR PROSTATE CANCER: FINAL ANALYSIS OF THE EQUINOXE STUDY

INTRODUCTION AND OBJECTIVES:The first few months of treatment for prostate cancer (PCa) are a difficult time for a couple. The degree of relational cohesion could have an effect on the experience of the disease. We analyzed the factors influencing the evolution of quality of life (QoL) in patients with PCa treated with hormone therapy for 6 months.METHODS:French prospective, multicenter, longitudinal and non-interventional study (NCT02630641). Urologists recruited partner-patient couples with PCa for whom hormone therapy was indicated. Data were collected at inclusion and after 6 months of treatment, on QoL (WHOQOL-BREF), perception of disease (B-IPQ), symptoms of the disease (QLQ-PR25) and perception of cohesion within the patient-partner relationship (dyadic adjustment, DAS-16). The results are presented as mean ± standard deviation. The final analysis included 492 patients (74.2 years ± 8.1), including 470 with a partner evaluation (70.5 ± 9.0 years).RESULTS:Patient QoL remained mostly stable (0 ±21.2)...