Electro-Oculographic and Electroretinographic Studies in HNPCC Gene Mutation Carriers

Purpose: To assess retinal function in HNPCC gene mutation carriers. Patients: 19 carriers (38 eyes) of HNPCC genes and controls. Methods: Electro-oculogram, standard flash electroretinogram and pattern electroretinogram (PERG) recordings were performed. Results: In the total group of HNPCC gene mutation carriers examined by oscillatory potentials, reduced amplitude (p Conclusion: Constitutional dysfunction of the inner retina appears to be a characteristic feature of HNPCC gene mutation carriers.