Treatment with lyophilized-albumin on cutaneous excision lesions

Summary This experiment studies the therapeutic effect of a new ointment based on lyophilized albumin extracted from egg on cutaneous excision lesion. The therapeutical assessments of the proposed ointment were done in vivo on the excisions excided on Wistar rat. The wounds were treated topically once a day, along 21 days. Clinical and macroscopic tests, tissue epitalization time wound contraction rate and histopathological examination were evaluated. The analyzes results revealed a significant healing effect of the new lyophized-albumin on the skin excision lesions by stimulation of the regeneration and the maturation of granulation tissue, antiinflammatory effect, collagenation effect at the lesion site resulting an incision-like mark hard to be seen without vicious healing in terms of both the clinic, macroscopic and histological point of view.