کلونیزاسیون استافیلوکوک اورئوس مقاوم به متیسیلین در کارکنان بهداشت و درمان ایران: یک بررسی سیستماتیک و متاآنالیز
2019
Staphylococcus aureus (SA) and especially methicillin-resistant staphylococcus aureus (MRSA) remains
a major cause of healthcare-associated infections worldwide. Health care workers (HCWs) may act as
reservoirs for transmission of MRSA to patients and other HCWs. The aim of this systematic review was
to investigate the prevalence of SA and MRSA colonization among HCWs in Iran. The used keywords for
searching were: “Iran”, “S. aureus” and “MRSA” conducted in PubMed, and Google Scholar, and two
national scientific databases and proceedings of recent national conferences. The studies related to SA
or MRSA prevalence in Iran published from 1993 to 2018 were included for review. Meta-analysis was
performed using the Open Meta (Analyst) software. Results showed that the prevalence of SA among
HCWs was 26% (95% CI=19.4-32.6%). The ratios of MRSA/total isolated SA and MRSA/total HCWs were
obtained 35.4% (95% CI=29.6-41.1%) and 7.6% (95% CI= 6.4-8.8%), respectively. Older studies showed
a higher prevalence compared to recent studies. The prevalence of nasal MRSA carriage among Iranian
HCWs was in a range between the rates reported in the U.S/European and African countries.
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