POS-477 CLINICAL PRESENTATIONS AND OUTCOMES OF RENAL DISEASE IN SARS-COV PATIENTS -A SINGLE CENTRE STUDY

Introduction: To study the clinical presentation and renal outcomes in SARS-COV infected patients with renal dysfunction Methods: In this single center observational study, SARS-COV infected inpatients referred to Nephrology Dept over a period of 4 months were classified in to 2 groups 1) De novo AKI and 2) Chronic kidney disease- includes CKD stage 1-4, CKD stage 5D (Maintenance Hemodialysis- MHD) and CKD 5T (Post kidney transplant- KTx) Results: In this observational study total 184 patients were included Mean age was 66 1 + 8 2 years, 68 % males 51% patients were diabetic, 79% hypertensive, 37 5% underlying heart disease (IHD + LVD) and 18 5% were having chronic lung disease 52% MHD group patient had no respiratory complaints Loose motion was most common in KTx group (32%) and altered sensorium was most common in MHD group (22%) Table-1: Presentation [Formula presented] Table-2A: Outcomes [Formula presented] Table 2B: Outcomes [Formula presented] Mechanical Ventilator required in 9% KTx, 35 % MHD, 42 % CKD and 55 % De novo AKI Conclusions: In this cohort of renal patients in the first 4 months of the COVID pandemic, it was observed that: 1 Typical respiratory complaints were less common among patients on MHD (p <0 05) 2 De novo AKI patients had higher mortality as compared to CKD patients (p <0 005) 3 Patients who required de novo initiation of RRT had a worse outcome Mortality in patients who were initiated on RRT was 93 % as compared to 19 5 % in MHD patients (p <0 0001) 4 Post kidney transplant patients had a better outcome in terms of mortality and complete GFR recovery as compared to other CKD Groups (p < 0 05) No conflict of interest