Quantitative analysis tools and correlative imaging applications for N-STORM

Super-resolution techniques have had a significant impact on our understanding of biological processes at the molecular level. However, one of the challenges to their broad utilization has been our limited ability to quantitatively analyze super-resolution images of complex biological tissues. In this Application Note, we highlight recent work by Dudok et al. utilizing Nikon's N-STORM system to develop new correlative imaging methods and quantitative analysis tools to study the mechanism of cannabinoid signaling in the brain.