Fluoride release from NaF- and AmF-impregnated toothpicks and dental flosses in vitro and in vivo.

The aim of this study was to determine the fluoride release from toothpicks and dental flosses in vitro and in vivo, and to evaluate various approximal administration methods. In vitro, a total of 23 commercially available toothpicks and dental flosses and 3 prototypes impregnated with sodium fluoride (NaF), amine fluoride (AmF), or a combination of these two were tested. Fluoride release was determined for up to 24 h using an ion‐specific electrode. A large variation was found between the products; most fluoride being released after 30 min. Generally speaking, toothpicks produced higher values than flosses. In vivo, the fluoride concentration in both treated and non‐treated approximal areas was evaluated after using 2 different types of toothpicks and 4 dental flosses and after different application methods—such as a fluoride gel and fluoride solution. The mean fluoride concentration in oral fluid was up to 10 times higher at the treated sites than at the non‐treated sites. Use of a fresh toothpick or a ...