S070 Phase 2 Study of Combretastatin A4 Phosphate (CA4P) in Patients With Advanced Anaplastic Thyroid Carcinoma (ATC)

S100P, and SAT remained elevated 2 weeks after surgery (P .05). Cytokeratin 14 (CK14) exhibited the greatest diminution in array expression pattern 2 weeks after surgery for OSCC and confirmed with qPCR. Using t test comparisons, postoperative CK14 gene expression was lower than before surgery (P .05) and no different vs control subjects. (P .05). Conclusions: While IL8, IL1B, DUSP1, HA3, OAZ1, S100P, and SAT hold promise for detecting OSCC in saliva, salivary CK14 mRNA can serve as a detection marker as well as a prognostic marker for therapeutic response to surgery in OSCC. Creating a saliva-based panel of these biomarkers could be used to diagnose and follow up patients with OSCC.