A randomised, double-blind, placebo-controlled trial, assessing the effect of a nutraceutical tablet in the management of stress in pet dogs

Abstract Canine stress-related behavioural issues are common welfare problems that can have negative implications on the quality of life of both the dog and owner. The effective management of canine stress is multifaceted, with emphasis on appropriate training, addressing environmental factors and the provision of supporting therapies such as nutraceuticals. In this randomised, double-blind, placebo-controlled study in 52 pet dogs with a history of stress behaviour, the nutraceutical CALMEX® was shown to significantly improve stress-related behavioural responses in dogs after 14 days of supplementation as determined by an owner-assessed questionnaire, with no significant change seen in the placebo group. Specifically, there was a significant difference found between placebo and CALMEX® in response to loud noise, with CALMEX® reducing owner-assessed stress scores by over a third in the 14 day study period. The results of this study suggest that CALMEX® is an effective product in the management of stress in pet dogs.