Synthesis, crystal structure and studies on the interaction with albumin of a new silver(I) complex based on 2‐(4‐nitrobenzenesulfonamido)benzoic acid

In the present work, the two-dimensional (2D) polymer poly[[μ4-2-(4-nitro­benzene­sulfonamido)­benzoato-κ4O1:O1:O1′:N6]silver(I)] (AgL), [Ag(C13H9N2O6S)]n, was obtained from 2-(4-nitro­benzene­sulfonamido)­benzoic acid (HL), C13H10N2O6S. FT–IR, 1H and 13C{1H} NMR spectroscopic analyses were used to characterize both compounds. The crystal structures of HL and AgL were determined by single-crystal X-ray diffraction. In the structure of HL, O—H⋯O hydrogen bonds between neighbouring mol­ecules result in the formation of dimers, while the silver(I) complex shows polymerization associated with the O atoms of three distinct deprotonated ligands (L−). Thus, the structure of the Ag complex can be considered as a coordination polymer consisting of a one-dimensional linear chain, constructed by carboxyl­ate bridging groups, running parallel to the b axis. Neighbouring polymeric chains are further bridged by Ag—C monohapto contacts, resulting in a 2D framework. Fingerprint analysis of the Hirshfeld surfaces show that O⋯H/H⋯O hydrogen bonds are responsible for the most significant contacts in the crystal packing of HL and AgL, followed by the H⋯H and O⋯C/C⋯O inter­actions. The Ag⋯Ag, Ag⋯O/O⋯Ag and Ag⋯C/C⋯Ag inter­actions in the Hirshfeld surface represent 12.1% of the total inter­actions in the crystal packing. Studies of the inter­actions of the compounds with human serum albumin (HSA) indicated that both HL and AgL inter­act with HSA.