Synthesis of 4-alkyl-substituted derivatives of cycloserine

1. A method for the synthesis of 4-isobutylcycloserine (4-amino-4-isobutyl-3-oxazolidone) has been developed. 2. 4-Methyl-, 4-propyl-, and 4-isobutyloxazoline-4-carbohydroxamic acids have been obtained from the corresponding α-alkylserines.