Abnormal Thymocyte Development and Neurofilament-Reactive Thymocytes in Thymoma

Myasthenia gravis (MG) is an autoimmune disease caused by autoantibodies against the acetylcholine receptor (AChR) at the neuromuscular junction [1, 2]. Mature CD4+ T-cells are involved in the production of these antibodies [3, 4]. The destruction at the neuromuscular endplates leads to the clinical symptom of muscle weakness.