PS8 - 39. Bcll glucocorticoid receptor polymorphism is associated with greater body fatness and higher insulin resistance: The Hoorn and CODAM Studies

Glucocorticoid receptor (GR) polymorphisms play an important role in the downstream effects of glucocorticoids (GCs). The BclI polymorphism has been shown to be associated with an enhanced GC sensitivity, which may result in greater abdominal obesity and its metabolic consequences.