609: The impact of prompt diagnosis and treatment on maternal and perinatal outcome in pregnant women with influenza A (H1N1)

singleton pregnancies after exclusion of long term steroid use and anomalies. Infectious outcomes were analyzed, including endometritis, chorioamnionitis, group B streptococcus (GBS), antenatal urinary tract infections (UTI), and wound infections. Infectious neonatal data were analyzed, including neonatal fever, sepsis, and pneumonia. Relative risk (RR) analyses were performed comparing normal weight (BMI 18.50-24.49) and underweight (BMI 50.00) patients with their corresponding neonatal data. Regression analyses were performed to account for confounding factors. RESULTS: Obese patients were at increased risk for wound infections (RR 1.96, 95% CI 1.55-2.47, P 0.0001), as well as endometritis (RR 1.62, 95% CI 1.19-2.22, P 0.0021), UTIs (RR 1.33, 95% CI 1.23-1.43, P 0.0001), and GBS (RR 1.22, 95% CI 1.18-1.26, P 0.0001). Interestingly, obesity was protective against chorioamnionitis with a RR of 0.83 (95% CI .074-0.92, P 0.0003). The multivariable logistic regression analysis showed that only race, age parity, and number of vaginal exams were risk factors for chorioamnionitis. Age, parity, and diabetes were risk factors for endometritis. Maternal obesity had no correlation with infectious neonatal outcomes. CONCLUSION: In addition to the predisposition to wound infections, obesity is a risk factor for endometritis, GBS, and antenatal UTIs. After regression analysis endometritis and chorioamnionitis do not have any significant association with obesity. Maternal obesity is not a risk factor for neonatal infections.