Identification of kinins releasing by pig pancreatic kallikrein from rabbit low molecular weight kininogen

: Pig pancreatic kallikrein is found to release kinins from LMrK with the rate of 800 mkg. eq. of bradykinin per min, per 1 mg of the enzyme. This kininogenase reaction is not accompanied by a ddep fragmentation of the kininogen molecule, because only a high molecular weight fragment which Mr is practically equal to that of intact LMrK (55-60 000), and a peptide identified as bradykinin, are found in hydrolysate. In the same conditions human salivary kallikrein is found to form kallidin from LMrK.