Genetic depletion of 5-HT increases central apnea frequency and duration and dampens arousal but does not impact the circadian modulation of these variables

Jason H. Mateika,Dragana Komnenov,Alexandru Pop,Donald M. Kuhn

Genetic depletion of 5-HT increases central apnea frequency and duration and dampens arousal but does not impact the circadian modulation of these variables

2019

Jason H. Mateika
Dragana Komnenov
Alexandru Pop
Donald M. Kuhn

The presence of serotonin (5-HT) in the central nervous system diminishes the frequency of central apneic events. This neuromodulator also moderates the duration of central apneic events and promot...

Keywords:

Central apnea
Anesthesia
Serotonin
Diabetes mellitus
5-HT receptor
Circadian rhythm
Chemistry
Central nervous system
Endocrinology
Internal medicine
Arousal

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