Tyrosine kinase inhibitor levels matter in treating chronic GVHD

We observed a possible concentration effect relationship for nilotinib on resolution of chronic Graft versus Host disease. These data suggest therapeutic drug monitoring might be useful for patients receiving tyrosine kinase inhibitors for chronic GVHD. We observed a possible concentration effect relationship for nilotinib on resolution of chronic Graft versus Host disease. These data suggest therapeutic drug monitoring might be useful for patients receiving tyrosine kinase inhibitors for chronic GVHD.